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The use of nitrogen in the pharmaceutical industry

2024/1/31

  In the pharmaceutical industry,nitrogen is used to replace dangerous or harmful air,creating a dry inert gas environment.Nitrogen can reduce oxygen content as oxygen may aid combustion or have a negative impact on product quality.Nitrogen helps maintain the sterility and cleanliness of drugs,and controls the oxygen content in work areas,laboratories,or entire facilities.Examples of using nitrogen in pharmaceutical processes include:

  •Filling active and high-purity pharmaceutical ingredients in the pharmaceutical process

  Replacing oxygen to prevent rapid oxidation and fire hazards

  •Determine the inert environment inside the vaccine sample bottle

  Inert gas packaging

  Nitrogen in packaging

  Nitrogen purification is a widely used technology that can be used to replace oxygen in packaging before sealing,to help preserve and protect products during transportation.Items that typically require the use of nitrogen in packaging include:

  Drugs packaged in vacuum molding

  Test kit for doctor's office

  Blood supplies

  Specimen container

  Sterile medical equipment

  Nitrogen gas used for product transfer

  In the pharmaceutical process,nitrogen is commonly used to move reaction mixtures from one container to another.It is crucial to use safe inert gases to transfer liquid or powdered pharmaceutical materials,as improper handling can lead to dangerous situations.Once in contact with oxygen or water vapor,many medicinal components may be damaged or even explode.

  Pharmaceutical nitrogen generator

  Approximately 78%of the air we breathe is nitrogen gas.By separating nitrogen molecules from other molecules in a clean and dry compressed air flow,higher purity nitrogen gas is produced,thereby achieving a continuous supply of high-purity nitrogen gas.Pharmaceutical companies that require a good supply of high-purity nitrogen can reduce costs by producing nitrogen independently,while enjoying the benefits of quality control and efficiency improvement.Autonomous nitrogen production can ensure that the company obtains nitrogen that meets purity requirements when needed,thereby improving production flexibility.

  Nitrogen and liquid nitrogen

  Approximately 80%of nitrogen is used in the form of gas rather than liquid.However,many companies still use bottled liquefied nitrogen gas.The main reason for liquefying nitrogen is for its ease of transportation,but generating liquid nitrogen requires a significant amount of energy consumption.Implementing autonomous nitrogen production can help pharmaceutical companies achieve significant cost savings ranging from 40%to 80%,depending on the current liquid nitrogen market prices.Autonomous nitrogen production also releases the space required to store nitrogen cylinders(full and empty).Moreover,a lower carbon footprint can bring additional benefits,which can help companies expand their industry development as environmental managers